OPTIONAL UPPER DIVISION GENERAL ELECTIVE Advanced Genetics course

Next semester I'll be teaching a new advanced Genetics and Genomics course that might interest some Physiology students (PLS 459A/559A). Please share the attached flyer with your students.

Although nominally focused on plant genetics, the course will cover eukaryotic genetics, genomics, and epigenetics. Here are some of the learning outcomes students can expect:

·  Use genotypic information to predict phenotype, including for complex traits and genetic interactions.

·  Use linkage data to identify causal alleles for a mutant phenotype or natural variant.

·  Describe the potential impact and limitations of genome editing.

·  Identify and annotate protein-coding genes from genomic sequence.

·  Provide examples of synthetic genes and their uses.

·  Describe the major components of a genome and how gene content varies between individuals and species.

·  Predict gene expression based on local chromatin modifications.

·  Provide an example of an epigenetic phenomenon and explain the underlying mechanism.

There is no requirement for any previous plant science course, but a strong understanding of basic Genetics is essential (eg, MCB 304, ECOL 320, PLS 312). Please let me know if you have any questions.

PLS 459A
Plant Genetics & Genomics!
Dr. Rebecca Mosher 

Offered Spring semesters

This course provides advanced coverage of genetics, including genomics and epigenetics, for advanced undergraduates or graduate students. Although plant systems will be emphasized, the course will benefit any student interested in modern genetics or genomics. Completion of PLS 312, MCB 304, ECOL 320, or other Genetics class is a required.

Students are will learn:
• how genetic analysis has led to biological discovery, including how reverse genetics and genome editing enable medical and biotech applications today
• to view genes in the context of a whole genome and how genes and genomes change over evolutionary time.
• how epigenetic mechanisms, including histone modification, DNA methylation, and transcriptional silencing influence how genes function

Thanks,

Becky

__________________________________

Dr. Rebecca Mosher

Associate Director and 

Associate Professor

The University of Arizona

The School of Plant Sciences

303 Forbes Bldg.

1140 E. South Campus Dr.

Tucson, AZ 85721-0036

USA

+1 520-626-4185

rmosher@email.arizona.edu

www.cals.arizona.edu/research/mosherlab